Product Details
Formal Name: 4-Iodo-3-nitrobenzamide
Alternate Names: BSI-201
Molecular Formula: C7H5IN2O3
Formula Weight: 292.03
CAS Number: 160003-66-7
Purity: >98%
Formulation: powder
Solubility: Soluble in DMSO (up to 15 mg/ml), or in Ethanol (up to 15 mg/ml).
Storage: RT
Stability: ≥ 1 year.
Applications
PARP inhibitor
Functions
Originally thought to be a PARP1 inhibitor but this is controversial. Inhibits ionizing radiation-induced single-stranded DNA break repair in lymphoid cell lines in vivo. Inhibits growth of certain breast cancer cell lines in vitro. Non-selectively modifies cysteine-containing proteins in tumor cells.
Application Procedures
First dissolved in DMSO (up to 15 mg/ml), or in Ethanol (up to 15 mg/ml), then diluted to aqueous buffer. Solutions in DMSO or Ethanol may be stored at -20°C for up to 3 months.