Tribioscience Deguelin, Akt inhibitor; Inhibits IκBα Kinase Activation (TBI2276)

Tribioscience Deguelin, Akt inhibitor; Inhibits IκBα Kinase Activation (TBI2276)

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Product Details

Molecular Formula: C₂₃H₂₂O₆

Formula Weight: 394.43

CAS Number: 522-17-8

Purity: >98%

Formulation: powder

Solubility: Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml).

Storage: RT

Stability: ≥ 2 years.

Applications

Akt inhibitor; Inhibits IκBα kinase activation

Functions

Inhibits Akt.  Induces apoptosis in a variety of cells. Displays cancer chemopreventive activity.  Cell permeable. Active in vivo.

Application Procedures

First dissolved in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml), then diluted to aqueous buffer. Solutions in DMSO may be stored at -20°C for up to 3 months.