First dissolved in DMSO, then diluted to aqueous buffer. Solutions in DMSO may be stored at -20°C for up to 1 month.
Tribioscience Bongkrekic Acid, Mitochondrial Permeability Pore Inhibitor (TBI2751)
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Tribioscience Bongkrekic Acid, Mitochondrial Permeability Pore Inhibitor (TBI2751)
Research Use Only. Not intended for human use.
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Product Details
Formal Name: 3-Carboxymethyl-17-methoxy-6,18,21-trimethyldocosa-2,4,8,12,18,20-heptaenedioic acid
Molecular Formula: C28H38O7 (free acid)
Formula Weight: 486.60
CAS Number: 11076-19-0
Purity: >98%
Formulation: Solution of 1mg/ml in Tris buffer
Solubility: Miscible with DMSO
Storage: -20°C
Stability: ≥ 1 year.
Applications
Mitochondrial permeability pore inhibitor
Functions
A potent inhibitory ligand of the mitochondrial adenine nucleotide translocase (ANT). Inhibits mitochondrial permeability transition pore opening. Delivery of bongkrekic acid to the mitochondria prevents apoptosis in HeLa cells.
Application Procedures