First dissolved in Water (greater than 25 mg/ml), then diluted to aqueous buffer. Solutions in distilled water may be stored at -20°C for up to 1 month.
Tribioscience Blasticidin S HCl, Antibiotic Selection Agent (TBI2830)
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Tribioscience Blasticidin S HCl, Antibiotic Selection Agent (TBI2830)
Research Use Only. Not intended for human use.
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Product Details
Formal Name: (S)-4-[[3-Amino-5-[(aminoiminomethyl)methylamino]-1-oxopentyl]amino]-1-(4-amino-2-oxo-1(2H)-pyrimidinyl)-1,2,3,4-tetradeoxy-β-D-erythro-hex-2-enopyranuronic acid hydrochloride
Molecular Formula: C17H26N8O5·HCl
Formula Weight: 458.90
CAS Number: 3513-03-9
Purity: >98%
Formulation: powder
Solubility: Soluble in Water (greater than 25 mg/ml).
Storage: -20°C
Stability: ≥ 1 year.
Applications
Antibiotic selection agent
Functions
A peptidyl nucleoside antibiotic inhibiting protein synthesis in bacteria and eukaryotes. Inhibits translation by trapping deformed tRNA on the ribosome. The ABC-type transporter NppA1A2BCD is required for uptake of blasticidin S and other peptidyl nucleoside antibiotics in Pseudomonas aeruginosa PA14. Selection agent for bis, bsr and bsd transformed cells.
Application Procedures