Tribioscience Anti-Mouse CTLA-4 Mouse Monoclonal Antibody (TBS10209)

Description: Cytotoxic T lymphocyte antigen-4 (CTLA-4), also known as CD152, is a regulatory molecule expressed on activated T cells and a subset of regulatory T cells (Tregs). CTLA-4 plays a crucial role in maintaining immune self-tolerance and homeostasis by down-regulating T-cell responses. It has been implicated in the immune dysregulation of several malignancies, including breast cancer, lung cancer, and melanoma, and is a target for cancer immunotherapy.

Applications:

• In vivo CTLA-4 neutralization
• Western blot

Molecular Weight: 150 kDa

Host: Mouse

Isotype: Mouse IgG2b

Concentration: 4 mg/ml

Purity: >95%

Formulation: PBS, pH 7.0, no stabilizers or preservatives.

Endotoxin: < 2EU/mg

Clonality: Monoclonal

Sterility: 0.2 µm filtered

Storage: Store at 4°C for one month. Store at -20°C for long-term storage.