Tribioscience Anti-Mouse CD25 Rat Monoclonal Antibody (TBS10226)

Description: Interleukin-2 receptor alpha (IL-2Rα) is a 55 kDa ligand-binding subunit of the interleukin-2 receptor (IL-2R) complex. This receptor is constitutively expressed at high levels on regulatory T (Treg) cells and at lower levels on natural killer (NK) cells and resting effector CD8+ T cells. IL-2Rα is also expressed in early thymocytes during T-cell development. It plays critical roles in lymphocyte differentiation, activation, and proliferation.

Applications:

• in vivo regulatory T cell depletion
• Flow cytometry

Molecular Weight: 150 kDa

Host: Rat

Isotype: Rat IgG1, lambda

Concentration: 4 mg/ml

Purity: >95%

Formulation: PBS, pH 7.0, no stabilizers or preservatives.

Endotoxin: < 2EU/mg

Clonality: Monoclonal

Sterility: 0.2 µm filtered

Storage: 4°C stable for up to one month. Store at -20°C for long-term.