TNNC1 Polyclonal Antibody Reactivity Mouse
SKU: E-AB-52316-200
TNNC1 Polyclonal Antibody Reactivity Mouse
| SKU # | E-AB-52316 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Applications | WB |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | WB |
| Clonality | Polyclonal |
| Immunogen | Full length fusion protein |
| Abbre | TNNC1 |
| Synonyms | Cardiac troponin C, TN-C, TNC, TNNC1, TNNI3, Tnnc1, Troponin C, Troponin C slow, Troponin C1 slow, slow skeletal and cardiac muscles, tnnc1a |
| Swissprot | |
| Calculated MW | 18 kDa |
| Observed MW | Refer to figures |
| Cellular Localization | Cytoskeleton, cardiac Troponin complex, troponin complex, Cytosol. |
| Concentration | 1.2 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Cancer, Cardiovascular, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:2000 |
Background
Troponin is a central regulatory protein of striated muscle contraction, and together with tropomyosin, is located on the actin filament. Troponin consists of 3 subunits: TnI, which is the inhibitor of actomyosin ATPase; TnT, which contains the binding site for tropomyosin; and TnC, the protein encoded by this gene. The binding of calcium to TnC abolishes the inhibitory action of TnI, thus allowing the interaction of actin with myosin, the hydrolysis of ATP, and the generation of tension.