TNFRSF11B Polyclonal Antibody Store at -20°C
SKU: E-AB-10508-200
TNFRSF11B Polyclonal Antibody Store at -20°C
| SKU # | E-AB-10508 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Applications | WB, IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human TNFRSF11B |
| Abbre | TNFRSF11B |
| Synonyms | MGC29565, OCIF, OPG, Osteoclastogenesis inhibitory factor, Osteoprotegerin, PDB5, TNF receptor superfamily member 11b, TNFRSF 11B, TNFRSF11B, TR 1, TR1, TR11B, Tumor necrosis factor receptor superfamily member 11B |
| Swissprot | |
| Calculated MW | 46 kDa |
| Cellular Localization | Secreted. |
| Concentration | 0.3 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Cardiovascular, Metabolism, Immunology, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:2000 |
| IHC | 1:25-1:100 |
Background
The protein encoded by this gene is a member of the TNF-receptor superfamily.This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption.This protein specifically binds to its ligand, osteoprotegerin ligand, both of which are key extracellular regulators of osteoclast development.Studies of the mouse counterpart also suggest that this protein and its ligand play a role in lymph-node organogenesis and vascular calcification.Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined.