TCOF1 Polyclonal Antibody Reactivity Human
SKU: E-AB-52784-200
TCOF1 Polyclonal Antibody Reactivity Human
| SKU # | E-AB-52784 |
| Reactivity | Human |
| Host | Rabbit |
| Applications | IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Fusion protein of human TCOF1 |
| Abbre | TCOF1 |
| Synonyms | MFD1, Mandibulofacial dysostosis, Nucleolar trafficking phosphoprotein, TCOF, TCOF 1, TCOF1, TCS, TCS1, Treacher Collins Franceschetti syndrome 1, Treacher Collins syndrome, Treacher Collins syndrome protein, Treacle, Treacle protein |
| Swissprot | |
| Cellular Localization | Nucleus>nucleolus. |
| Concentration | 0.9 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Cancer, Signal transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:40-1:200 |
Background
This gene encodes a nucleolar protein with a LIS1 homology domain. The protein is involved in ribosomal DNA gene transcription through its interaction with upstream binding factor (UBF). Mutations in this gene have been associated with Treacher Collins syndrome, a disorder which includes abnormal craniofacial development. Multiple transcript variants encoding different isoforms have been found for this gene.