SUMO2/3/4 Polyclonal Antibody
SKU: E-AB-12439-200
SUMO2/3/4 Polyclonal Antibody
| SKU # | E-AB-12439 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Applications | WB, IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human SUMO2/SUMO3/SUMO4 |
| Abbre | SUMO2/3/4 |
| Synonyms | HSMT3, IDDM5, SMT3A, SMT3B, SMT3H1, SMT3H2, SMT3H4, SUMO-3, SUMO-4, SUMO3, Smt3A, Smt3B, dJ281H8.4 |
| Swissprot | |
| Calculated MW | 12 kDa |
| Observed MW | Refer to figures |
| Cellular Localization | Extracellular region or secreted, extracellular exosome, Nucleus, nucleoplasm, nucleus, PML body, Other locations: cytoplasm, kinetochore. |
| Concentration | 0.4 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cell Biology |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:2000 |
| IHC | 1:100-1:300 |
Background
This gene encodes a protein that is a member of the SUMO (small ubiquitin-like modifier) protein family. It functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, this protein is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. It is not active until the last two amino acids of the carboxy-terminus have been cleaved off. Numerous pseudogenes have been reported for this gene. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.