SPCS2 Polyclonal Antibody Reactivity Mouse
SKU: E-AB-52301-200
SPCS2 Polyclonal Antibody Reactivity Mouse
| SKU # | E-AB-52301 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Applications | WB, IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Fusion protein of human SPCS2 |
| Abbre | SPCS2 |
| Synonyms | Microsomal signal peptidase 25 kDa subunit, SPCS2, SPase 25 kDa subunit, Signal peptidase complex subunit 2, Signal peptidase complex subunit 2 homolog (S. cerevisiae) |
| Swissprot | |
| Calculated MW | 25 kDa |
| Observed MW | Refer to figures |
| Cellular Localization | Microsome membrane. Endoplasmic reticulum membrane. |
| Concentration | 1.3 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Signal transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:2000 |
| IHC | 1:25-1:100 |
Background
SPCS2 (signal peptidase complex subunit 2), also known as SPC25 or microsomal signal peptidase 25 kDa subunit, is a 226 amino acid multi-pass membrane protein that localizes to both the microsome and the endoplasmic reticulum (ER), and belongs to the SPCS (signal peptidase complex subunit) family. Existing as a component of the microsomal signal peptidase complex which consists of five members, SPCS2 removes signal peptides from nascent proteins as they are translocated into the lumen of the ER. The gene encoding SPCS2 is located on human chromosome 11, which houses over 1,400 genes and comprises nearly 4% of the human genome.