SIGLEC6 Polyclonal Antibody
SKU: E-AB-52953-200
SIGLEC6 Polyclonal Antibody
| SKU # | E-AB-52953 |
| Reactivity | Human |
| Host | Rabbit |
| Applications | WB, IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Fusion protein of human SIGLEC6 |
| Abbre | SIGLEC6 |
| Synonyms | CD327, CD33 antigen-like 1, CD33L, CD33L1, CD33L2, CDw327, OB-BP1, OBBP1, Obesity-binding protein 1, SIGL6, SIGLEC6, Sialic acid-binding Ig-like lectin 6, Siglec-6 |
| Swissprot | |
| Calculated MW | 50 kDa |
| Observed MW | Refer to figures |
| Cellular Localization | Secreted and Cell membrane. |
| Concentration | 0.78 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Immunology |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:2000 |
| IHC | 1:40-1:200 |
Background
The SIGLEC6 gene to 19q13.3, which is where the CD33 gene is located.Putative adhesion molecule that mediates sialic-acid dependent binding to cells.Binds to alpha-2,6-linked sialic acid.The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface.Expressed at high levels in placenta (cyto- and syncytiotrophoblastic cells) and at lower levels in spleen, peripheral blood leukocytes (predominantly B-cells) and small intestine.