SIGLEC5 Polyclonal Antibody Store at -20°C
SKU: E-AB-14839-200
SIGLEC5 Polyclonal Antibody Store at -20°C
| SKU # | E-AB-14839 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Applications | WB, IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human SIGLEC5 |
| Abbre | SIGLEC5 |
| Synonyms | CD170, CD170 antigen, CD33 antigen-like 2, CD33L2, OB-BP2, OB-binding protein 2, OBBP2, Obesity-binding protein 2, Sialic acid binding Ig-like lectin 5, Sialic acid binding immunoglobulin-like lectin 5, Sialic acid-bin, Sialic acid-binding Ig-like lectin 5, mSiglec-F |
| Swissprot | |
| Calculated MW | 61 kDa |
| Cellular Localization | Membrane. |
| Concentration | 0.3 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Immunology |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:200-1:1000 |
| IHC | 1:50-1:200 |
Background
This gene encodes a member of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. These cell surface lectins are characterized by structural motifs in the immunoglobulin (Ig)-like domains and sialic acid recognition sites in the first Ig V set domain. The encoded protein is a member of the CD33-related subset of Siglecs and inhibits the activation of several cell types including monocytes, macrophages and neutrophils. Binding of group B Streptococcus (GBS) to the encoded protein plays a role in GBS immune evasion