SF3A3 Polyclonal Antibody Reactivity Rat
SKU: E-AB-40169-200
SF3A3 Polyclonal Antibody Reactivity Rat
| SKU # | E-AB-40169 |
| Reactivity | Rat |
| Host | Rabbit |
| Applications | IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Rat |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant human Splicing factor 3A subunit 3 protein |
| Abbre | SF3A3 |
| Synonyms | PRP 9, PRP9, PRPF 9, PRPF9, Pre mRNA splicing factor SF3a, Pre mRNA splicing factor SF3a (60kD), SAP 61, SAP61, SF3A3, SF3a60, Spliceosome associated protein 61, Splicing factor 3a subunit 3, Splicing factor 3a subunit 3 60kDa |
| Swissprot | |
| Cellular Localization | Nucleus speckle. |
| Concentration | 1 mg/mL |
| Buffer | PBS with 0.05% proclin 300, 1% protective protein and 50% glycerol,pH7.4 |
| Purification Method | Antigen Affinity Purification |
| Research Areas | Cancer, Epigenetics and Nuclear Signaling |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:50-1:100 |
Background
This gene encodes subunit 3 of the splicing factor 3a protein complex. The splicing factor 3a heterotrimer includes subunits 1, 2 and 3 and is necessary for the in vitro conversion of 15S U2 snRNP into an active 17S particle that performs pre-mRNA splicing. Subunit 3 interacts with subunit 1 through its amino-terminus while the zinc finger domain of subunit 3 plays a role in its binding to the 15S U2 snRNP. This gene has a pseudogene on chromosome 20. Alternative splicing results in multiple transcript variants.