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SDHB Monoclonal Antibody Stored at -20°C
SDHB Monoclonal Antibody Stored at -20°C
Elabscience Biotechnology

SDHB Monoclonal Antibody Stored at -20°C

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SKU: ELAB6974-R-0.1
$ 511.95

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SDHB Monoclonal Antibody Stored at -20°C

 

Product Details

Host Rabbit
Reactivity Human
Applications IHC-P
Synonyms SDHB
Cellular Localization Cytoplasm
Tissue Specificity gastric stromal tumor
Storage The concentrated should be stored at -20°C protecting from light,Valid for 12 months.
Shipping Ice bag

 

Background

Succinate dehydrogenase (SDH) complex is a key respiratory enzyme composed of four subunits, SDHA, SDHB, SDHC and SDHD. SDHB was expressed in the cytoplasm of normal cells, but absent in abnormal cells. SDHB mutations can lead to oncogenesis of pheochromocytoma, causing a class of tumors called succinate dehydrogenase-deficient tumors, including hereditary paraganglioma and hereditary pheochromocytoma, succinate dehydrogenase-deficient renal carcinoma, and succinate dehydrogenase-deficient gastrointestinal stromal tumor (GIST).