RUVBL2 Polyclonal Antibody Reactivity Human
SKU: E-AB-52644-200
RUVBL2 Polyclonal Antibody Reactivity Human
| SKU # | E-AB-52644 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Applications | IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Fusion protein of human RUVBL2 |
| Abbre | RUVBL2 |
| Synonyms | 48 kDa TATA box-binding protein-interacting protein, 48 kDa TBP-interacting protein, 48-kDa TATA box-binding protein-interacting protein, 48-kDa TBP-interacting protein, 51 kDa erythrocyte cytosolic protein, CGI-46, EC=3.6.1.-, ECP-51, ECP51, Erythrocyte cytosolic |
| Swissprot | |
| Cellular Localization | Nucleus matrix. Nucleus>nucleoplasm. Cytoplasm. Membrane. Mainly localized in the nucleus, associated with nuclear matrix or in the nuclear cytosol. Although it is also present in the cytoplasm and associated with the cell membranes. |
| Concentration | 0.84 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Cancer, Epigenetics and Nuclear Signaling |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:30-1:150 |
Background
This gene encodes the second human homologue of the bacterial RuvB gene. Bacterial RuvB protein is a DNA helicase essential for homologous recombination and DNA double-strand break repair. Functional analysis showed that this gene product has both ATPase and DNA helicase activities. This gene is physically linked to the CGB/LHB gene cluster on chromosome 19q13.3, and is very close (55 nt) to the LHB gene, in the opposite orientation.