Recombinant Mouse TGM2/Transglutaminase 2 Protein (His Tag)
SKU: PKSM041171-50
Recombinant Mouse TGM2/Transglutaminase 2 Protein (His Tag)
| SKU # | PKSM041171 |
| Expression Host | HEK293 Cells |
Description
| Synonyms | Protein-glutamine gamma-glutamyltransferase 2, TGase-2, Tgm2, Tissue transglutaminase, Transglutaminase C |
| Species | Mouse |
| Expression Host | HEK293 Cells |
| Sequence | Ala2-Ala686 |
| Accession | P21981 |
| Calculated Molecular Weight | 78.0 kDa |
| Observed Molecular Weight | 70-90 kDa |
| Tag | C-His |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
| Shipping | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C. |
| Formulation | Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 20% Glycerol, pH 7.5. |
| Reconstitution | Not Applicable |
Background
Protein-glutamine gamma-glutamyltransferase 2 (TGM2) is a 78-kDa, calcium dependent enzyme,It belongs to the transglutaminase superfamily and transglutaminase family. The protein encoded by this TGM2 gene acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. TGM2 is the autoantigen implicated in celiac disease. Two transcript variants encoding different isoforms have been found for this gene