Recombinant Mouse L-Selectin/SELL Protein (His Tag) Purity >95%
SKU: PKSM041308-50
Recombinant Mouse L-Selectin/SELL Protein (His Tag) Purity >95%
| SKU # | PKSM041308 |
| Expression Host | HEK293 Cells |
Description
| Synonyms | CD62 antigen-like family member L, CD62L, L-selectin, LECAM-1, LECAM1, Leukocyte adhesion molecule 1, Lnhr, Ly-22, Ly-m22, Lyam-1, Lyam1, Lymph node homing receptor, Lymphocyte antigen 22, Sell |
| Species | Mouse |
| Expression Host | HEK293 Cells |
| Sequence | Trp39-Asn332 |
| Accession | P18337 |
| Calculated Molecular Weight | 61 kDa |
| Observed Molecular Weight | 80-120 kDa |
| Tag | C-His |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4. Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Reconstitution | Please refer to the printed manual for detailed information. |
Background
L-Selectin is a member of a family of Selectin that is transiently expressed on vascular endothelial cells in response to IL-1 beta and TNF-alpha. L-Selectin (Leukocyte Selectin, LAM-1, LECAM-1, LECCAM-1, TQ1, Leu-8, MEL-14 antigen, DREG, lymph node homing receptor, CD62L) is expressed constitutively on a wide variety of leukocytes and mediates a number of leukocyte-endothelial interactions, including the binding of lymphocytes to HEV of peripheral lymph node high endothelial venules (HEV), neutrophil rolling, and leukocyte attachment to cytokine-treated endothelium in vitro.