Recombinant Human SLAM family member 1/SLAMF1/CD150 (C-6His-Avi) Biotinylated
SKU: PKSH034001-100
Recombinant Human SLAM family member 1/SLAMF1/CD150 (C-6His-Avi) Biotinylated
| SKU # | PKSH034001 |
| Expression Host | HEK293 Cells |
Description
| Synonyms | CDw, IPO, SLAMF, SLAMF1, CD150, CDw150, SLAM, IPO-3, Signaling Lymphocytic Activation Molecule, IPO-3 |
| Species | Human |
| Expression Host | HEK293 Cells |
| Sequence | Ala21-Pro237 |
| Accession | Q13291 |
| Calculated Molecular Weight | 27.1 kDa |
| Observed Molecular Weight | 45-65 kDa |
| Tag | C-His-Avi |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Reconstitution | Please refer to the printed manual for detailed information. |
Background
SLAM-induced signal-transduction events in T-lymphocytes are different from those in B-cells. Two modes of SLAM signaling are likely to exist: one in which the inhibitor SH2D1A acts as a negative regulator and another in which protein-tyrosine phosphatase 2C (PTPN11)-dependent signal transduction operates.