Recombinant Human ODC1 Protein (His & T7 Tag)
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Recombinant Human ODC1 Protein (His & T7 Tag)
| SKU # | PKSH032837 |
| Expression Host | E.coli |
Description
| Synonyms | ODC1, Ornithine decarboxylase |
| Species | Human |
| Expression Host | E.coli |
| Sequence | Met 1-Val461 |
| Accession | P11926 |
| Calculated Molecular Weight | 53.5 kDa |
| Observed Molecular Weight | 25 &58 kDa |
| Tag | N-T7 & C-His |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 90 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
| Shipping | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C. |
| Formulation | Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, pH 8.0. |
| Reconstitution | Not Applicable |
Background
Ornithine decarboxylase (ODC1) is an enzyme which belongs to the Orn/Lys/Arg decarboxylase class-II family. ODC1 is the rate-limiting enzyme of the polyamine biosynthesis pathway which catalyzes ornithine to putrescine. The activity level for the enzyme varies in response to growth-promoting stimuli and exhibits a high turnover rate in comparison to other mammalian proteins.