Recombinant Human DEFB104A Protein
SKU: PKSH033265-50
Recombinant Human DEFB104A Protein
| SKU # | PKSH033265 |
| Expression Host | E.coli |
Description
| Synonyms | BD-4, Beta-Defensin 104, Beta-Defensin 4, DEFB-4, DEFB104, DEFB104A, DEFB104B, DEFB4, Defensin Beta 104, hBD-4 |
| Species | Human |
| Expression Host | E.coli |
| Sequence | Glu23-Pro72 |
| Accession | Q8WTQ1 |
| Calculated Molecular Weight | 6.0 kDa |
| Observed Molecular Weight | 9 kDa |
| Tag | None |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Formulation | Lyophilized from a 0.2 μm filtered solution of 20mM PB, 130mM NaCl, pH 7.4. Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Reconstitution | Please refer to the printed manual for detailed information. |
Background
Defensins are cationic peptides. It is an important ingredient of the innate immune system. β-defensins are expressed on some leukocytes and epithelial surfaces. Four human β-Defensins have been identified to date: BD-1, BD-2, BD-3 and BD-4. β-defensins contain a six-cysteine motif, they forms three intra-molecular disulfide bonds. β-defensins are also chemoattractant towards immature dendritic cells and memory T cells. The β-defensin proteins are expressed as the C-terminal portion of precursors; they are released by proteolytic cleavage of a signal sequence.