Recombinant Cynomolgus FGL1 (C-Avi-6His) Biotinylated
SKU: PKSQ050098-100
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Recombinant Cynomolgus FGL1 (C-Avi-6His) Biotinylated
| SKU # | PKSQ050098 |
| Expression Host | HEK293 Cells |
Description
| Synonyms | FGL1, Fibrinogen-like protein 1, HFREP-1, HP-041, Hepassocin, LFIRE-1 |
| Species | Cynomolgus macaques |
| Expression Host | HEK293 Cells |
| Sequence | Leu23-Ile312 |
| Accession | A0A2K5X990 |
| Calculated Molecular Weight | 34.8 kDa |
| Observed Molecular Weight | 36 kDa |
| Tag | C-Avi-His |
| Bio-activity | Not validated for activity |
Properties
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg of the protein as determined by the LAL method. |
| Storage | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
| Shipping | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C. |
| Formulation | Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 300mM NaCl, 10% Glycerol, 2mM EDTA, pH 8.0. |
| Reconstitution | Not Applicable |
| Modification | Biotinylated |
Background
Fibrinogen-like protein 1(FGL1) is also known as HP-041, Hepassocin, HFREP-1, LFIRE-1, is a liver-specific secreted protein belonging to the fibronogen superfamily, whose members share a fibrinogen domain at their C-termini. It is secreted by the liver and functions as a mitogen for hepatocytes. Hepassocin may play a role in the development of hepatocellular carcinomas. Hepassocin is a disulfide-linked homodimeric protein with a C-terminal fibrinogen domain. It is reported that it is a major immune inhibitory ligand of LAG-3.