RCHY1 Polyclonal Antibody Reactivity Human
SKU: E-AB-52167-200
RCHY1 Polyclonal Antibody Reactivity Human
| SKU # | E-AB-52167 |
| Reactivity |
Human, Mouse |
| Host | Rabbit |
| Applications | WB, IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Fusion protein of human RCHY1 |
| Abbre | RCHY1 |
| Synonyms | ARNIP, Androgen receptor N terminal interacting protein, Androgen receptor N-terminal-interacting protein, CH-rich-interacting match with PLAG1, CHIMP, E3 ubiquitin-protein ligase Pirh2, hARNIP, hPirh2, p53 induced protein with a RING H2 domain, p53-induced RING-H |
| Swissprot | |
| Calculated MW | 30 kDa |
| Observed MW | Refer to figures |
| Cellular Localization | Nucleus. Nucleus speckle. Cytoplasm. |
| Concentration | 0.84 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Cancer, Cell Biology |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:2000 |
| IHC | 1:50-1:200 |
Background
The protein encoded by this gene has ubiquitin ligase activity. It mediates E3-dependent ubiquitination and proteasomal degradation of target proteins, including TP53, HDAC1 and CDKN1B, thus regulating their levels and cell cycle progression. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.