PTPRA Polyclonal Antibody Reactivity Human
SKU: E-AB-52203-200
PTPRA Polyclonal Antibody Reactivity Human
| SKU # | E-AB-52203 |
| Reactivity |
Human, Mouse, Rat |
| Host | Rabbit |
| Applications | WB |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| Clonality | Polyclonal |
| Immunogen | Fusion protein of human PTPRA |
| Abbre | PTPRA |
| Synonyms | HEPTP, HLPR, HPTP alpha, HPTPA, HPTPalpha, LRP, Leukocyte common antigen related peptide, Prot, Protein tyrosine phosphatase alpha, Protein tyrosine phosphatase receptor type A, Protein tyrosine phosphatase receptor type alpha polypeptide, Protein tyrosine phosphate |
| Swissprot | |
| Calculated MW | 91 kDa |
| Observed MW | Refer to figures |
| Cellular Localization | Membrane. |
| Concentration | 0.6 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Signal transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:2000 |
Background
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. This PTP has been shown to dephosphorylate and activate Src family tyrosine kinases, and is implicated in the regulation of integrin signaling, cell adhesion and proliferation. Three alternatively spliced variants of this gene, which encode two distinct isoforms, have been reported.