PTGER4 Polyclonal Antibody Store at -20°C
SKU: E-AB-15622-200
PTGER4 Polyclonal Antibody Store at -20°C
| SKU # | E-AB-15622 |
| Reactivity | Human |
| Host | Rabbit |
| Applications | WB |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | WB |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human PTGER4 |
| Abbre | PTGER4 |
| Synonyms | EP 4, EP4, EP4R, MGC126583, PE2R4, PGE receptor EP4 subtype, PGE2 receptor EP4 subtype, PTGE, PTGER 2, PTGER 4, Prostaglandin E receptor 4, Prostaglandin E receptor 4 subtype EP4, Prostaglandin E2 receptor, Prostaglandin E2 receptor EP4 subtype, Prostanoid EP4 receptor |
| Swissprot | |
| Calculated MW | 53 kDa |
| Cellular Localization | Cell membrane. |
| Concentration | 0.6 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:2000 |
Background
The protein encoded by this gene is a member of the G-protein coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2). This receptor can activate T-cell factor signaling. It has been shown to mediate PGE2 induced expression of early growth response 1 (EGR1), regulate the level and stability of cyclooxygenase-2 mRNA, and lead to the phosphorylation of glycogen synthase kinase-3. Knockout studies in mice suggest that this receptor may be involved in the neonatal adaptation of circulatory system, osteoporosis, as well as initiation of skin immune responses.