PSMA6 Polyclonal Antibody Reactivity Human
SKU: E-AB-53111-200
PSMA6 Polyclonal Antibody Reactivity Human
| SKU # | E-AB-53111 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Applications | WB, IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Fusion protein of human PSMA6 |
| Abbre | PSMA6 |
| Synonyms | 27 kDa prosomal protein, IOTA, MGC22756, MGC2333, MGC23846, Macropain iota chain, Macropain subunit iota, Multicatalytic endopeptidase complex iota chain, PROS 27, PROS-27, PROS27, Prosomal P27K protein, Protea, Proteasome (prosome macropain) subunit alpha type 6, p27K |
| Swissprot | |
| Calculated MW | 27 kDa |
| Observed MW | Refer to figures |
| Cellular Localization | Cytoplasm. Nucleus. |
| Concentration | 1.14 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Cancer, Cell Biology |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:1000-1:5000 |
| IHC | 1:50-1:200 |
Background
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Multiple transcript variants encoding several different isoforms have been found for this gene. A pseudogene has been identified on the Y chromosome.