PSMA3 Polyclonal Antibody Reactivity Human
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PSMA3 Polyclonal Antibody Reactivity Human
| SKU # | E-AB-52718 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Applications | WB, IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Fusion protein of human PSMA3 |
| Abbre | PSMA3 |
| Synonyms | HC8, MGC12306, MGC32631, Macropain subunit C8, Multicatalytic endopeptidase complex subunit C8, Proteasome (prosome macropain) subunit alpha type 3, Proteasome alpha 3 subunit, Proteasome component C8, Proteasome subunit alpha typ, Proteasome subunit alpha type 3 |
| Swissprot | |
| Calculated MW | 28 kDa |
| Observed MW | Refer to figures |
| Cellular Localization | Cytoplasm. Nucleus. |
| Concentration | 0.54 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Cancer, Cell Biology |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:2000 |
| IHC | 1:40-1:200 |
Background
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Two alternative transcripts encoding different isoforms have been identified.