PRPF8 Polyclonal Antibody
SKU: E-AB-19744-200
PRPF8 Polyclonal Antibody
| SKU # | E-AB-19744 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Applications | WB |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | WB |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human PRPF8 |
| Abbre | PRPF8 |
| Synonyms | S. cerevisiae, homolog of, 220 kDa U5 snRNP specific protein, 220 kDa U5 snRNP-specific protein, Apoptosis regulated protein 1, Apoptosis regulated protein 2, HPRP8, Pre mRNA processing factor 8, Pre mRNA-processing factor 8, Pre-mRNA-processing-splicing fa, p220 |
| Swissprot | |
| Calculated MW | 274 kDa |
| Observed MW | Refer to figures |
| Cellular Localization | Nucleus speckle. |
| Concentration | 0.6 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Cancer, Epigenetics and Nuclear Signaling, Neuroscience |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:2000 |
Background
Pre-mRNA splicing occurs in 2 sequential transesterification steps. The protein encoded by this gene is a component of both U2- and U12-dependent spliceosomes, and found to be essential for the catalytic step II in pre-mRNA splicing process. It contains several WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to yeast Prp8 protein. This gene is a candidate gene for autosomal dominant retinitis pigmentosa.