PRMT7 Polyclonal Antibody Store at -20°C
SKU: E-AB-10554-200
PRMT7 Polyclonal Antibody Store at -20°C
| SKU # | E-AB-10554 |
| Reactivity | Human |
| Host | Rabbit |
| Applications | WB |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | WB |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human PRMT7 |
| Abbre | PRMT7 |
| Synonyms | ANM7, FLJ10640, Histone-arginine N-methyltransferase PRMT7, KIAA1933, Myelin basic protein arginine N methyltransferase, OTTHUMP00000174863, PRMT7, Protein arginine N-, Protein arginine methyltransferase 7, [Myelin basic protein]-arginine N-methyltransferase PRMT7 |
| Swissprot | |
| Calculated MW | 78 kDa |
| Cellular Localization | Cytoplasm, cytosol. Nucleus. |
| Concentration | 0.2 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Epigenetics and Nuclear Signaling |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:2000 |
Background
Protein arginine methyltransferase 7 is a protein that in humans is encoded by the PRMT7 gene.Arginine methylation is an apparently irreversible protein modification catalyzed by arginine methyltransferases, such as PMT7, using S-adenosylmethionine (AdoMet) as the methyl donor.Arginine methylation is implicated in signal transduction, RNA transport, and RNA splicing.May be involved in etoposide-induced cytotoxicity, a chemotherapeutic agent frequently used for testicular cancer and small-cell lung cancer that can cause cytotoxicity in the treatment of other cancers.Down-regulation confers increased sensitivity to the Top1 inhibitor camptothecin (CPT).