PPP2R1A Polyclonal Antibody Reactivity Human
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PPP2R1A Polyclonal Antibody Reactivity Human
| SKU # | E-AB-52989 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Applications | WB |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | WB |
| Clonality | Polyclonal |
| Immunogen | Fusion protein of human PPP2R1A |
| Abbre | PPP2R1A |
| Synonyms | protein phosphatase, 2AAA, 6330556D22Rik, Alpha isoform of regulatory subunit A, DKFZp470L0914, MGC128399, MGC786, MGC83000, MGC95083, Medium tumor antigen-associated 61 kDa protein, PP2A, PP2A Aalpha, PP2A subunit A isoform PR65-alpha, PP2A subunit A isoform R1-alph |
| Swissprot | |
| Calculated MW | 65 kDa |
| Observed MW | Refer to figures |
| Cellular Localization | Cytoplasm. Chromosome>centromere. Centromeric localization requires the presence of BUB1. |
| Concentration | 1.08 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Cancer, Signal transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:1000-1:5000 |
Background
This gene encodes a constant regulatory subunit of protein phosphatase 2. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. This gene encodes an alpha isoform of the constant regulatory subunit A. Alternatively spliced transcript variants have been described.