PPP2CA Polyclonal Antibody Store at -20°C
SKU: E-AB-11494-200
PPP2CA Polyclonal Antibody Store at -20°C
| SKU # | E-AB-11494 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Applications | WB, IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human PPP2CA |
| Abbre | PPP2CA |
| Synonyms | PP2A alpha, PP2A-alpha, PP2AA, PP2Aalpha, PP2Ac, PP2CA, PP2Calpha, PPP2CA, Protein phos, Protein phosphatase 2, Protein phosphatase 2 (formerly 2A) catalytic subunit alpha isoform, Protein phosphatase 2 catalytic subunit alpha isoform, alpha isozyme, catalytic subunit |
| Swissprot | |
| Calculated MW | 36 kDa |
| Cellular Localization | Cytoplasm. Nucleus. Chromosome>centromere. Cytoplasm>cytoskeleton>spindle pole. In prometaphase cells, but not in anaphase cells, localizes at centromeres. During mitosis, also found at spindle poles. Centromeric localization requires the presence of SGOL2. |
| Concentration | 0.2 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Cell Biology, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:1000-1:5000 |
| IHC | 1:25-1:100 |
Background
This gene encodes the phosphatase 2A catalytic subunit. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. This gene encodes an alpha isoform of the catalytic subunit.