Phospho-FOXO1/3 (Ser322/S325) Polyclonal Antibody
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Phospho-FOXO1/3 (Ser322/S325) Polyclonal Antibody
| SKU # | E-AB-21016 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Applications | WB, IHC-p |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC-p |
| Clonality | Polyclonal |
| Immunogen | Synthesized peptide derived from human FoxO1/3 around the phosphorylation site of Ser322/S325 |
| Synonyms | AF6q21 protein, FKHR, FKHRL1, FOXO1, FOXO1A, FOXO3, FOXO3A, Forkhead box protein O1, Forkhead box protein O1A, Forkhead box protein O3, Forkhead in rhabdomyosarcoma, Forkhead in rhabdomyosarcoma-like 1 |
| Swissprot | |
| Calculated MW | 70 kDa |
| Observed MW | 97 kDa |
| Cellular Localization | Cytosol, Mitochondrion, mitochondrion, Nucleus, nucleoplasm, nucleus, Other locations: cytoplasm, membrane. |
| Concentration | 1 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 0.5% protein protectant and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Epigenetics and Nuclear Signaling, Metabolism, Neuroscience, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:2000 |
| IHC | 1:100-1:300 |
Background
FOXO1 (Forkhead Box O1) is a Protein Coding gene. Diseases associated with FOXO1 include Rhabdomyosarcoma 2, Alveolar and Rhabdomyosarcoma. Among its related pathways are Constitutive Signaling by AKT1 E17K in Cancer and Common Cytokine Receptor Gamma-Chain Family Signaling Pathways. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and chromatin binding. An important paralog of this gene is FOXO3. FOXO3 (Forkhead Box O3) is a Protein Coding gene. Diseases associated with FOXO3 include Rhabdomyosarcoma and Lung Cancer. Among its related pathways are Development IGF-1 receptor signaling and Constitutive Signaling by AKT1 E17K in Cancer. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and protein kinase binding. An important paralog of this gene is FOXO1.