PEMT Polyclonal Antibody Reactivity Human
SKU: E-AB-52055-200
PEMT Polyclonal Antibody Reactivity Human
| SKU # | E-AB-52055 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Applications | WB |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | WB |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human PEMT |
| Abbre | PEMT |
| Synonyms | PEAMT, PEMPT, PEMT, PEMT2, PNMT, Phosphatidylethanolamine N-methyltransferase, phosphatidylethanolamine N methyltransferase |
| Swissprot | |
| Calculated MW | 22 kDa |
| Observed MW | Refer to figures |
| Cellular Localization | Endoplasmic reticulum membrane. Mitochondrion membrane. Found in endoplasmic reticulum where most PEMT activity is generated and in mitochondria. |
| Concentration | 2.4 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Cancer, Metabolism, Signal transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:1000-1:5000 |
Background
Phosphatidylcholine (PC) is the most abundant mammalian phospholipid. This gene encodes an enzyme which converts phosphatidylethanolamine to phosphatidylcholine by sequential methylation in the liver. Another distinct synthetic pathway in nucleated cells converts intracellular choline to phosphatidylcholine by a three-step process. The protein isoforms encoded by this gene localize to the endoplasmic reticulum and mitochondria-associated membranes. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms.