PAWR Polyclonal Antibody Store at -20°C
SKU: E-AB-15819-200
PAWR Polyclonal Antibody Store at -20°C
| SKU # | E-AB-15819 |
| Reactivity | Human |
| Host | Rabbit |
| Applications | WB |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | WB |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human PAWR |
| Abbre | PAWR |
| Synonyms | 2310001G03Rik, PAR 4, PAR-4, PAWR, PRKC Apoptosis WT1 Regulator, PRKC apoptosis WT1 regulator protein, Pawr, Prostate apoptosis response 4 protein, Prostate apoptosis response protein 4, Transcriptional repressor Par-4-lik, prostate apoptosis response protein PAR-4 |
| Swissprot | |
| Calculated MW | 37 kDa |
| Cellular Localization | Cytoplasm. Nucleus. Mainly cytoplasmic in absence of apoptosis signal and in normal cells. Nuclear in most cancer cell lines. Nuclear entry seems to be essential but not sufficient for apoptosis (By similarity). Nuclear localization includes nucleoplasm and PML nuclear bodies. |
| Concentration | 0.3 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Cell Biology, Epigenetics and Nuclear Signaling, Metabolism |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:2000 |
Background
The tumor suppressor WT1 represses and activates transcription. The protein encoded by this gene is a WT1-interacting protein that itself functions as a transcriptional repressor. It contains a putative leucine zipper domain which interacts with the zinc finger DNA binding domain of WT1. This protein is specifically upregulated during apoptosis of prostate cells.