PADI4 Polyclonal Antibody Reactivity Human
SKU: E-AB-52164-200
PADI4 Polyclonal Antibody Reactivity Human
| SKU # | E-AB-52164 |
| Reactivity |
Human |
| Host | Rabbit |
| Applications | WB, IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Fusion protein of human PADI4 |
| Abbre | PADI4 |
| Synonyms | EC 3.5.3.15, HL 60 PAD, HL-60 PAD, PAD, PAD 4, PADI 4, PADI 5, PADI H protein, PADI4, PADI5, PDI 4, PDI 5, PDI4, PDI5, Padi4, Peptidyl arginine deiminase type IV, Peptidyl arginine deiminase type V, Peptidylarginine deiminase IV, Protein arginine, Protein arginine deiminase |
| Swissprot | |
| Calculated MW | 74 kDa |
| Observed MW | Refer to figures |
| Cellular Localization | Cytoplasm. Nucleus. Cytoplasmic granule. Cytoplasmic granules of eosinophils and neutrophils. |
| Concentration | 0.6 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Cancer, Epigenetics and Nuclear Signaling, Metabolism, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:2000 |
| IHC | 1:40-1:200 |
Background
This gene is a member of a gene family which encodes enzymes responsible for the conversion of arginine residues to citrulline residues. This gene may play a role in granulocyte and macrophage development leading to inflammation and immune response. PADI4 plays a role in the epigenetics, the deimination of arginines on histones 3 and 4 can act antagonistically to arginine methylation. The protein may be found in oligomers and binds 5 calcium ions per subunit. It catalyses the reaction: Protein L-arginine + H2O = protein L-citrulline + NH3.