ORC4 Polyclonal Antibody Reactivity Human
SKU: E-AB-52717-200
ORC4 Polyclonal Antibody Reactivity Human
| SKU # | E-AB-52717 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Applications | IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Fusion protein of human ORC4 |
| Abbre | ORC4 |
| Synonyms | S. cerevisiae, homolog of, subunit 4, FLJ46668, HSORC4, ORC 4, ORC 4L, ORC 4P, ORC4, ORC4L, ORC4L protein, ORC4P, Origin recognition comp, Origin recognition complex, Origin recognition complex subunit 4, Origin recognition complex subunit 4 (yeast homolog) like |
| Swissprot | |
| Cellular Localization | Nucleus. |
| Concentration | 1.26 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Cancer, Epigenetics and Nuclear Signaling |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:40-1:200 |
Background
The origin recognition complex (ORC) is a highly conserved six subunit protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. This gene encodes a subunit of the ORC complex. Several alternatively spliced transcript variants, some of which encode the same protein, have been reported for this gene.