NCF2 Polyclonal Antibody
SKU: E-AB-11447-200
NCF2 Polyclonal Antibody
| SKU # | E-AB-11447 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Applications | WB, IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human NCF2 |
| Abbre | NCF2 |
| Synonyms | 67 kDa neutrophil oxidase factor, Chronic granulomatous disease autosomal 2, FLJ93058, NADPH oxidase activator 2, NCF-2, NCF2, Ncf2, Neutrophil NADPH oxida, Neutrophil cytosol factor 2, Neutrophil cytosolic factor 2 (65kD, autosomal 2), chronic granulomatous disease |
| Swissprot | |
| Calculated MW | 60 kDa |
| Cellular Localization | Cytoplasm. |
| Concentration | 0.5 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Metabolism, Immunology |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:200-1:1000 |
| IHC | 1:50-1:200 |
Background
This gene encodes neutrophil cytosolic factor 2, the 67-kilodalton cytosolic subunit of the multi-protein NADPH oxidase complex found in neutrophils. This oxidase produces a burst of superoxide which is delivered to the lumen of the neutrophil phagosome. Mutations in this gene, as well as in other NADPH oxidase subunits, can result in chronic granulomatous disease, a disease that causes recurrent infections by catalase-positive organisms. Alternative splicing results in multiple transcript variants encoding different isoforms.