MYOZ2 Polyclonal Antibody Reactivity Human
SKU: E-AB-52584-200
MYOZ2 Polyclonal Antibody Reactivity Human
| SKU # | E-AB-52584 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Applications | WB |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | WB |
| Clonality | Polyclonal |
| Immunogen | Full length fusion protein |
| Abbre | MYOZ2 |
| Synonyms | C4orf5, CMH16, CS 1, CS1, Calcineurin binding protein calsarcin 1, Calsarcin 1, Calsarcin-1, Calsarcin1, FATZ related protein 2, FATZ-related protein 2, MYOZ 2, MYOZ2, Muscle specific protein, Myozenin-2, Myozenin2 |
| Swissprot | |
| Calculated MW | 30 kDa |
| Observed MW | Refer to figures |
| Cellular Localization | Cytoplasm>myofibril>sarcomere>Z line. Colocalizes with ACTN1 and PPP3CA at the Z-line of heart and skeletal muscle. |
| Concentration | 1.08 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Cardiovascular, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:40-1:200 |
Background
MYOZ2 (Myozenin 2) is a Protein Coding gene. Diseases associated with MYOZ2 include Cardiomyopathy, Hypertrophic, 16 and Myoz2-Related Familial Hypertrophic Cardiomyopathy. GO annotations related to this gene include actin binding and telethonin binding. An important paralog of this gene is MYOZ1.The protein encoded by this gene belongs to a family of sarcomeric proteins that bind to calcineurin, a phosphatase involved in calcium-dependent signal transduction in diverse cell types. These family members tether calcineurin to alpha-actinin at the z-line of the sarcomere of cardiac and skeletal muscle cells, and thus they are important for calcineurin signaling. Mutations in this gene cause cardiomyopathy familial hypertrophic type 16, a hereditary heart disorder.