MTHFS Polyclonal Antibody Reactivity Human
SKU: E-AB-52848-200
MTHFS Polyclonal Antibody Reactivity Human
| SKU # | E-AB-52848 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Applications | IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Fusion protein of human MTHFS |
| Abbre | MTHFS |
| Synonyms | 10-methenyl-tetrahydrofolate synthetase, 10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase), 5, 5 10 methenyl tetrahydrofolate synthetase, 5 formyltetrahydrofolate cyclo ligase, 5-formyltetrahydrofolate cyclo-ligase, FLJ30410, HsT19 |
| Swissprot | |
| Cellular Localization | Cytoplasm. |
| Concentration | 1.68 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Cancer, Metabolism, Signal transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:50-1:300 |
Background
The protein encoded by this gene is an enzyme that catalyzes the conversion of 5-formyltetrahydrofolate to 5,10-methenyltetrahydrofolate, a precursor of reduced folates involved in 1-carbon metabolism. An increased activity of the encoded protein can result in an increased folate turnover rate and folate depletion. Three transcript variants encoding two different isoforms have been found for this gene.