MSE PRO 2-Dicyclohexylphosphino-2',6'-diisopropoxybiphenyl (RuPhos), 98% Purity

$ 174⁹⁵
Save $ 18⁸⁵

MSE PRO™ 2-Dicyclohexylphosphino-2',6'-diisopropoxybiphenyl (RuPhos), 98% Purity

MSE PRO™ 2-Dicyclohexylphosphino-2',6'-diisopropoxybiphenyl (RuPhos) is a versatile ligand for many Pd-catalyzed coupling reactions of secondary arylamines and alkylamine, such as Pd-catalyzed Negishi cross-coupling reaction of (hetero)arylchlorides, Pd-catalyzed regiospecific synthesis of N-aryl benzimidazoles, Pd-catalyzed C-N coupling reaction of secondary aryl- and alkyl-amines, Pd-catalyzed Suzuki-Miyaura coupling of aryl chloride and NHC-boranes. etc.

MSE Supplies offers various catalysts and ligands of coupling reaction. Please contact us for customization or bulk orders.

Technical Specifications:

CAS No.	787618-22-8
EC No.	616-653-5
Chemical name	2-Dicyclohexylphosphino-2',6'-diisopropoxybiphenyl
Synonym(s)	RuPhos 2-Dicyclohexylphosphino-2',6'-di-i-propoxy-1,1'-biphenyl
Molecular formula	C₃₀H₄₃O₂P
Pack size	25 g (CM1303) 100 g (CM1304)
Molecular weight	466.64 g/mol
Purity	98 %
Melting point	123-124 °C
Solubility	Chloroform (slightly), DMSO (slightly), methanol (slightly)
Appearance	White powder
Storage	Keep in dark place, sealed in dry, room temperature

References:

[1] van den Hoogenband, A., Lange, J. H., Terpstra, J. W., Koch, M., Visser, G. M., Visser, M., ... & Jastrzebski, J. T. (2008). Ruphos-mediated Suzuki cross-coupling of secondary alkyl trifluoroborates. Tetrahedron Letters, 49(26), 4122-4124.

[2] Dasaradhan, C., Kumar, Y. S., Prabakaran, K., Khan, F. R. N., Jeong, E. D., & Chung, E. H. (2015). Efficient and convenient copper-free Pd (OAc) 2/Ruphos-catalyzed Sonogashira coupling in the preparation of corfin analogues. Tetrahedron letters, 56(6), 784-788.