MCPH1 Polyclonal Antibody Reactivity Human
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MCPH1 Polyclonal Antibody Reactivity Human
| SKU # | E-AB-52481 |
| Reactivity | Human |
| Host | Rabbit |
| Applications | IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Fusion protein of human MCPH1 |
| Abbre | MCPH1 |
| Synonyms | BRCT repeat inhibitor of TERT expression 1, BRIT 1, FLJ12847, Hypothetical protein FLJ12847, MCPH 1, MCPH1, MCT, Microcephalin, Microcephalin 1, Microcephaly primary autosomal recessive 1 |
| Swissprot | |
| Cellular Localization | Cytoplasm>cytoskeleton>centrosome. |
| Concentration | 0.5 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Cancer, Epigenetics and Nuclear Signaling |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:30-1:150 |
Background
This gene encodes a DNA damage response protein. The encoded protein may play a role in G2/M checkpoint arrest via maintenance of inhibitory phosphorylation of cyclin-dependent kinase 1. Mutations in this gene have been associated with primary autosomal recessive microcephaly 1 and premature chromosome condensation syndrome. Alternatively spliced transcript variants have been described.