MCL1 Polyclonal Antibody Storage Store at -20°C
SKU: E-AB-31988-200
MCL1 Polyclonal Antibody Storage Store at -20°C
| SKU # | E-AB-31988 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Applications | WB, IHC-p |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC-p |
| Clonality | Polyclonal |
| Immunogen | Synthesized peptide derived from the Internal region of human Mcl-1 |
| Abbre | MCL1 |
| Synonyms | BCL2 related, BCL2L3, Bcl 2 related protein EAT/mcl1, Bcl-2-like protein 3, Bcl-2-related protein EAT/mcl1, Bcl2-L-3, EAT, Induced myeloid leukemia cell differentiation protein Mcl 1, Induced myeloid leukemia cell differentiation protein Mcl-1, MCL 1, MCL1, MCL1-ES |
| Swissprot | |
| Calculated MW | 37 kDa |
| Observed MW | 37 kDa
|
| Cellular Localization | Membrane. Cytoplasm. Mitochondrion. Nucleus>nucleoplasm. Cytoplasmic, associated with mitochondria. |
| Concentration | 1 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer, 0.5% protein protectant and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Cell Biology, Metabolism |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:2000 |
| IHC | 1:100-1:300 |
Background
This gene encodes an anti-apoptotic protein, which is a member of the Bcl-2 family. Alternative splicing results in multiple transcript variants. The longest gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene products (isoform 2 and isoform 3) promote apoptosis and are death-inducing.