MC2R Polyclonal Antibody
SKU: E-AB-12555-200
MC2R Polyclonal Antibody
| SKU # | E-AB-12555 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Applications | WB |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | WB |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human MC2R |
| Abbre | MC2R |
| Synonyms | ACTH receptor, ACTH-R, ACTHR, Adrenocorticotropic hormone receptor, Adrenocorticotropin receptor, Corticotropin receptor, MC2 receptor, MC2-R, MC2R, Melanocortin 2 receptor, Melanocortin 2 receptor (adrenocorticotropic hormone), Melanocortin receptor 2 |
| Swissprot | |
| Calculated MW | 34 kDa |
| Cellular Localization | Cell membrane. |
| Concentration | 0.5 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Cardiovascular, Metabolism, Neuroscience, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:1000-1:5000 |
Background
MC2R encodes one member of the five-member G-protein associated melanocortin receptor family. Melanocortins (melanocyte-stimulating hormones and adrenocorticotropic hormone) are peptides derived from pro-opiomelanocortin (POMC). MC2R is selectively activated by adrenocorticotropic hormone, whereas the other four melanocortin receptors recognize a variety of melanocortin ligands. Mutations in MC2R can result in familial glucocorticoid deficiency.