MAD2L1BP Polyclonal Antibody Store at -20°C
SKU: E-AB-14202-200
MAD2L1BP Polyclonal Antibody Store at -20°C
| SKU # | E-AB-14202 |
| Reactivity | Human |
| Host | Rabbit |
| Applications | WB, IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human MAD2L1BP |
| Abbre | MAD2L1BP |
| Synonyms | CMT2, Caught by MAD2 protein, KIAA0110, MAD2L1 binding protein, MAD2L1 binding protein isoform 2, MAD2L1-binding protein, MD2BP, MGC11282, Mad2l1bp, OTTHUMP00000016496, RP1 261G23.6, dJ261G23.1 |
| Swissprot | |
| Calculated MW | 31 kDa |
| Cellular Localization | Nucleus. Cytoplasm>cytoskeleton>spindle. During early mitosis, unevenly distributed throughout the nucleoplasm. From metaphase to anaphase, concentrated on the spindle. |
| Concentration | 0.9 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Cell Biology |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:2000 |
| IHC | 1:50-1:200 |
Background
The protein encoded by this gene was identified as a binding protein of the MAD2 mitotic arrest deficient-like 1 (MAD2/MAD2L1). MAD2 is a key component of the spindle checkpoint that delays the onset of anaphase until all the kinetochores are attached to the spindle. This protein may interact with the spindle checkpoint and coordinate cell cycle events in late mitosis. Alternatively spliced transcript variants encoding distinct isoforms have been observed.