Lgals3 Polyclonal Antibody Reactivity Human
SKU: E-AB-40655-100
Lgals3 Polyclonal Antibody Reactivity Human
| SKU # | E-AB-40655 |
| Reactivity | Human, mouse, Rat |
| Host | Rabbit |
| Applications | WB |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, mouse, Rat |
| Applications | WB |
| Clonality | Polyclonal |
| Immunogen | Recombinant Rat Lgals3 protein expressed by E.coli |
| Abbre | Lgals3 |
| Synonyms | 35 kDa lectin, CBP 35, GALBP, Gal-3, Galactose-specific lectin 3, Galectin-3, IgE-binding protein, L-31, Laminin-binding protein, Lectin L-29, MAC2, Mac-2 antigen, LGALS3 |
| Swissprot | |
| Calculated MW | 26 kDa |
| Observed MW | 28 kDa |
| Concentration | 1 mg/mL |
| Buffer | PBS with 0.05% proclin 300, 1% protective protein and 50% glycerol,pH7.4 |
| Purification Method | Antigen Affinity Purification |
| Research Areas | Neuroscience, Cell Biology |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:250-1:500 |
Background
Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis. In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells. Together with TRIM16, coordinates the recognition of membrane damage with mobilization of the core autophagy regulators ATG16L1 and BECN1 in response to damaged endomembranes.