KIF2A Polyclonal Antibody Reactivity Human
SKU: E-AB-53005-200
KIF2A Polyclonal Antibody Reactivity Human
| SKU # | E-AB-53005 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Applications | WB, IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Fusion protein of human KIF2A |
| Abbre | KIF2A |
| Synonyms | CDCBM3, HK2, KIF2, KIF2A, KNS2, Kinesin 2, Kinesin heavy chain 2, Kinesin heavy chain member 2, Kinesin heavy chain member 2A, Kinesin like protein KIF2A, Kinesin-2, Kinesin-like protein KIF2A, M Kinesin |
| Swissprot | |
| Calculated MW | 80 kDa |
| Observed MW | Refer to figures |
| Cellular Localization | Cytoplasm. Cytoplasm>cytoskeleton>centrosome. Cytoplasm>cytoskeleton>spindle pole. Cytoplasm>cytoskeleton>spindle. Localized to the spindle microtubules and spindle poles from prophase to metaphase. Efficient targeting to spindle microtubules and spindle poles requires the kinase activity of PLK1. Recruited to mitotic spindles by interaction with PSRC1. |
| Concentration | 1.14 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Antigen affinity purification |
| Research Areas | Cancer, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:2000 |
| IHC | 1:50-1:100 |
Background
The protein encoded by this gene is a plus end-directed motor required for normal mitotic progression. The encoded protein is required for normal spindle activity during mitosis and is necessary for normal brain development. Several transcript variants encoding different isoforms have been found for this gene.