KIAA1524 Polyclonal Antibody Store at -20°C
SKU: E-AB-14875-200
KIAA1524 Polyclonal Antibody Store at -20°C
| SKU # | E-AB-14875 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Applications | WB |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | WB |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human KIAA1524 |
| Abbre | KIAA1524 |
| Synonyms | CIP2A, Cancerous Inhibitor of Protein Phosphatase 2A, Cancerous inhibitor of PP2A, FLJ12850, Kiaa1524, MGC163436, Protein CIP2A, p90, p90 autoantigen |
| Swissprot | |
| Calculated MW | 102 kDa |
| Cellular Localization | Membrane. Cytoplasm. Slightly concentrates in the perinuclear region. |
| Concentration | 0.5 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:2000 |
Background
Protein CIP2A also known as cancerous inhibitor of PP2A (CIP2A) is a protein that in humans is encoded by the KIAA1524 gene.Protein phosphatase 2A (PP2A) is a cellular tumor suppressor which inhibits cell proliferation and transformation of normal cells to malignant cancer cells.Inhibition of PP2A activity is a prerequisite for human cell transformation.However, the in vivo mechanisms by which PP2A activity is inhibited in spontaneously transformed human cancer cells have been unclear.