ITPR3 Polyclonal Antibody Store at -20°C
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ITPR3 Polyclonal Antibody Store at -20°C
| SKU # | E-AB-13346 |
| Reactivity | Human |
| Host | Rabbit |
| Applications | IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human ITPR3 |
| Abbre | ITPR3 |
| Synonyms | 4, 5 trisphosph, 5 trisphosphate receptor type 3, 5-trisphosphate receptor, 5-trisphosphate receptor type 3, FLJ36205, IP3 receptor, IP3 receptor isoform 3, IP3R, IP3R 3, IP3R3, ITPR 3, ITPR3, Inositol 1, InsP3R3, Type 3 inositol 1 |
| Swissprot | |
| Cellular Localization | Endoplasmic reticulum membrane. |
| Concentration | 1 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Neuroscience, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:50-1:200 |
Background
This gene encodes a receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium. The receptor contains a calcium channel at the C-terminus and the ligand-binding site at the N-terminus. Knockout studies in mice suggest that type 2 and type 3 inositol 1,4,5-trisphosphate receptors play a key role in exocrine secretion underlying energy metabolism and growth.