IRF1 Polyclonal Antibody Store at -20°C
SKU: E-AB-12522-200
IRF1 Polyclonal Antibody Store at -20°C
| SKU # | E-AB-12522 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Applications | WB, IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide of human IRF1 |
| Abbre | IRF1 |
| Synonyms | IRF 1, IRF-1, IRF1, Interferon regulatory factor 1, Interferon regulatory factor 1 isoform +I9, Interferon regulatory factor 1 isoform d78, Interferon regulatory factor 1 isoform delta4, Interferon regulatory factor 1 isoform delta7, MAR, MAR1 |
| Swissprot | |
| Calculated MW | 37 kDa |
| Cellular Localization | Nucleus. |
| Concentration | 0.4 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Cardiovascular, Epigenetics and Nuclear Signaling |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| WB | 1:500-1:2000 |
| IHC | 1:50-1:200 |
Background
IRF1 encodes interferon regulatory factor 1, a member of the interferon regulatory transcription factor (IRF) family. IRF1 serves as an activator of interferons alpha and beta transcription, and in mouse it has been shown to be required for double-stranded RNA induction of these genes. IRF1 also functions as a transcription activator of genes induced by interferons alpha, beta, and gamma. Further, IRF1 has been shown to play roles in regulating apoptosis and tumor-suppressoion.