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IRAK4 Polyclonal Antibody Store at -20°C
SKU: E-AB-10409-200
IRAK4 Polyclonal Antibody Store at -20°C
| SKU # | E-AB-10409 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Applications | IHC |
Product Details
| Isotype | IgG |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Applications | IHC |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human IRAK4 |
| Abbre | IRAK4 |
| Synonyms | IL-1 receptor-associated kinase 4, IPD1, IRAK 4, IRAK-4, IRAK4, IRAK4 mutated form 1, Interleukin 1 receptor associated kinase 4 mutant form 1, Interleukin-1 receptor-associated kinase 4, Interleukin1 receptor associated kinase 4, LOC 51135, NY REN , NY REN 64 |
| Swissprot | |
| Cellular Localization | Cytosol, Endosome membrane, Extracellular region or secreted, extracellular space, Nucleus, Plasma Membrane, Other locations: cytoplasm. |
| Concentration | 0.6 mg/mL |
| Buffer | Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol. |
| Purification Method | Affinity purification |
| Research Areas | Cancer, Cardiovascular, Immunology, Signal Transduction |
| Conjugation | Unconjugated |
| Storage | Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles. |
| Shipping | The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended. |
Related Reagents
| Applications | Recommended Dilution |
| IHC | 1:50-1:200 |
Background
This gene encodes a kinase that activates NF-kappaB in both the Toll-like receptor (TLR) and T-cell receptor (TCR) signaling pathways. The protein is essential for most innate immune responses. Mutations in this gene result in IRAK4 deficiency and recurrent invasive pneumococcal disease. Multiple transcript variants encoding different isoforms have been found for this gene.